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Advanced Transcriptomics

Consultation with our core staff is required before projects are accepted and is provided free-of-charge. Services listed include:

 

  • sample QC using a Nexcellom automated fluorescent cell counter

  • library preparation

  • library QC using an Agilent Fragment Analyzer, Qubit 3 fluorometer and/or qPCR.

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We have a close partnership with the CWRU Genomics Core which operates a high-throughput sequencing facility.

Technology
Submission
Requirements
Service
List
Single Cell Gene Expression

We offer single cell library preparation using 10X Genomics technology targeting up to 10,000 cells or nuclei per sample. The Chromium Single Cell platform offers incredible flexibility with the ability to profile fixed tissue, cells, and nuclei. ​

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Single cell resolution to capture the full heterogeneity of your sample

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  • Characterize diverse cell populations

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  • Identify unique cell states and gene expression signatures

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  • Integrate data to uncover complex disease or developmental processes

Single Cell Multiomic Readout

Simultaneously capture gene expression and chromatin state from the same cell to profile both the transcriptome and epigenome.

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  • Investigate epigenetic remodeling and gene regulatory networks.

  • Increase your power to characterize cell types and states

Gene expression analysis can be coupled with additional modalities to generate multi-omics datasets at single cell resolution

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Services

  • 3'/5' Single Cell Gene Expression​

  • 3' Fixed RNA profiling

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